pyPESTO

ICB-DCM/pyPESTO — python Parameter EStimation TOolbox

Widely applicable and highly customizable toolbox for parameter estimation.
Fides

fides-dev/fides — Reliable Trust-Region Optimization

Trust-Region Optimization featuring various Hessian approximation schemes.
AMICI

AMICI-dev/AMICI — Advanced Multilanguage Interface to CVODES and IDAS

High performance ordinary differential equation solver for simulation and sensitivity computation.
PEtab

PEtab-dev/PEtab — Parameter Estimation using tab-separated values files

Data format for specifying parameter estimation problems in systems biology.